FHL5

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Four and a half LIM domains protein 5 is a protein that in humans is encoded by the FHL5 gene.[5]

PDBOrtholog search: PDBe RCSB
AliasesFHL5, ACT, dJ393D12.2, 1700027G07Rik, FHL-5, four and a half LIM domains 5
Quick facts Available structures, PDB ...
FHL5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFHL5, ACT, dJ393D12.2, 1700027G07Rik, FHL-5, four and a half LIM domains 5
External IDsOMIM: 605126; MGI: 1913192; HomoloGene: 23230; GeneCards: FHL5; OMA:FHL5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001170807
NM_020482
NM_001322466
NM_001322467

NM_021318
NM_001355498
NM_001379528

RefSeq (protein)

NP_001164278
NP_001309395
NP_001309396
NP_065228

NP_067293
NP_001342427
NP_001366457

Location (UCSC)Chr 6: 96.56 – 96.62 MbChr 4: 25.2 – 25.24 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene.[5]

Interactions

FHL5 has been shown to interact with CREB1[6] and CAMP responsive element modulator.[6][7]

References

Further reading

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