FRMPD4

Protein-coding gene in humans From Wikipedia, the free encyclopedia

FERM and PDZ domain containing 4 is a protein that in humans is encoded by the FRMPD4 gene. [5]

PDBOrtholog search: PDBe RCSB
AliasesFRMPD4, PDZD10, PDZK10, FERM and PDZ domain containing 4, MRX104
Quick facts Available structures, PDB ...
FRMPD4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFRMPD4, PDZD10, PDZK10, FERM and PDZ domain containing 4, MRX104
External IDsOMIM: 300838; MGI: 3042378; HomoloGene: 45843; GeneCards: FRMPD4; OMA:FRMPD4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014728

RefSeq (protein)
Location (UCSC)Chr X: 12.14 – 12.72 MbChr X: 166.25 – 167.36 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a multi-domain (WW, PDZ, FERM) containing protein. Through its interaction with other proteins (such as PSD-95), it functions as a positive regulator of dendritic spine morphogenesis and density, and is required for the maintenance of excitatory synaptic transmission.

References

Further reading

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