FTSJ3

pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 is an enzyme, an O-methyltransferase, that in humans is encoded by the FTSJ3 gene.^[5]

AliasesFTSJ3, EPCS3, SPB1, FtsJ homolog 3, FtsJ RNA methyltransferase homolog 3, FtsJ RNA 2'-O-methyltransferase 3

External IDsOMIM: 618411; MGI: 1860295; HomoloGene: 5451; GeneCards: FTSJ3; OMA:FTSJ3 - orthologs

Chr.Chromosome 17 (human)^[1]

End63,830,012 bp^[1]

Quick facts Identifiers, Aliases ...

FTSJ3
Identifiers
Aliases	FTSJ3, EPCS3, SPB1, FtsJ homolog 3, FtsJ RNA methyltransferase homolog 3, FtsJ RNA 2'-O-methyltransferase 3
External IDs	OMIM: 618411; MGI: 1860295; HomoloGene: 5451; GeneCards: FTSJ3; OMA:FTSJ3 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q23.3 Start 63,819,433 bp[1] End 63,830,012 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 E1|11 68.89 cM Start 106,139,968 bp[2] End 106,146,905 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte sural nerve tendon of biceps brachii stromal cell of endometrium gastric mucosa right ovary right adrenal gland right lobe of thyroid gland body of uterus canal of the cervix Top expressed in tail of embryo genital tubercle epiblast ventricular zone yolk sac blastocyst embryo zygote morula morula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function methyltransferase activity transferase activity rRNA methyltransferase activity protein binding RNA binding rRNA (uridine-2'-O-)-methyltransferase activity rRNA (guanine) methyltransferase activity Cellular component nucleus nucleolus preribosome, large subunit precursor preribosome, small subunit precursor Biological process rRNA processing methylation RNA methylation ribosome biogenesis maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA methylation enzyme-directed rRNA 2'-O-methylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 117246 56095 Ensembl ENSG00000108592 ENSMUSG00000020706 UniProt Q8IY81 Q9DBE9 RefSeq (mRNA) NM_017647 NM_025310 RefSeq (protein) NP_060117 NP_079586 Location (UCSC) Chr 17: 63.82 – 63.83 Mb Chr 11: 106.14 – 106.15 Mb PubMed search [3] [4]
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