Frizzled-10

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Frizzled-10 (Fz-10) is a protein that in humans is encoded by the FZD10 gene.[5][6] Fz-10 has also been designated as CD350 (cluster of differentiation 350).

AliasesFZD10, CD350, FZ-10, Fz10, FzE7, hFz10, frizzled class receptor 10
End130,165,740 bp[1]
Quick facts FZD10, Identifiers ...
FZD10
Identifiers
AliasesFZD10, CD350, FZ-10, Fz10, FzE7, hFz10, frizzled class receptor 10
External IDsOMIM: 606147; MGI: 2136761; HomoloGene: 21411; GeneCards: FZD10; OMA:FZD10 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007197

NM_175284

RefSeq (protein)

NP_009128

NP_780493

Location (UCSC)Chr 12: 130.16 – 130.17 MbChr 5: 128.68 – 128.68 Mb
PubMed search[3][4]
Wikidata
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Function

This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.[6]

References

Further reading

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