Frizzled-9

FZD9
Identifiers
Aliases	FZD9, CD349, FZD3, frizzled class receptor 9
External IDs	OMIM: 601766; MGI: 1313278; HomoloGene: 2619; GeneCards: FZD9; OMA:FZD9 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	73,436,120 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	135,280,084 bp
RNA expression pattern
	Top expressed in
	cartilage tissue; ; muscle of thigh; ; gastrocnemius muscle; ; amygdala; ; cingulate gyrus; ; anterior cingulate cortex; ; prefrontal cortex; ; C1 segment; ; hypothalamus; ; right frontal lobe;
	Top expressed in
	rib; ; myotome; ; soleus muscle; ; lumbar subsegment of spinal cord; ; lumbar spine; ; ventricular zone; ; stria vascularis; ; plantaris muscle; ; larynx; ; extensor digitorum longus muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; signal transducer activity; Wnt-protein binding; protein heterodimerization activity; transmembrane signaling receptor activity; G protein-coupled receptor activity; Wnt-activated receptor activity;
Cellular component	cytoplasm; membrane; plasma membrane; cell surface; perinuclear region of cytoplasm; filopodium membrane; endoplasmic reticulum membrane; Golgi apparatus; mitochondrial membranes; integral component of membrane; postsynapse; glutamatergic synapse;
Biological process	G protein-coupled receptor signaling pathway; Wnt signaling pathway; nervous system development; multicellular organism development; cell surface receptor signaling pathway; learning or memory; neuroblast proliferation; B cell differentiation; signal transduction; ossification; release of cytochrome c from mitochondria; positive regulation of bone mineralization; positive regulation of apoptotic process; negative regulation of neuron apoptotic process; regulation of cytosolic calcium ion concentration; negative regulation of mitochondrial depolarization; negative regulation of necroptotic process; positive regulation of canonical Wnt signaling pathway; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; regulation of skeletal muscle acetylcholine-gated channel clustering; negative regulation of skeletal muscle acetylcholine-gated channel clustering; bone regeneration; positive regulation of neural precursor cell proliferation; non-canonical Wnt signaling pathway; canonical Wnt signaling pathway; postsynapse organization; regulation of postsynaptic cytosolic calcium ion concentration;
	Sources:Amigo / QuickGO
Orthologs
	8326
	14371
	ENSG00000188763
	ENSMUSG00000049551
	O00144
	Q9R216
	NM_003508
	NM_010246
	NP_003499
	NP_034376
	Wikidata
View/Edit Human	View/Edit Mouse

Frizzled-9 (Fz-9) is a protein that in humans is encoded by the FZD9 gene.^[5]^[6]^[7] Fz-9 has also been designated as CD349 (cluster of differentiation 349).