Fenestrel

Fenestrel
Clinical data
Other names	Demethoxycarbestrol; NSC-86465; 2-methyl-3-ethyl-4-phenyl-δ4-cyclohexenecarboxylic acid
ATC code	None;
Identifiers
	IUPAC name 5-Ethyl-6-methyl-4-phenylcyclohex-3-ene-1-carboxylic acid;
CAS Number	7698-97-7;
PubChem CID	24371;
ChemSpider	22786;
UNII	LEC4215V9R;
CompTox Dashboard (EPA)	DTXSID20864106 ;
Chemical and physical data
Formula	C16H20O2
Molar mass	244.334 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC1C(C(CC=C1C2=CC=CC=C2)C(=O)O)C;
	InChI InChI=1S/C16H20O2/c1-3-13-11(2)14(16(17)18)9-10-15(13)12-7-5-4-6-8-12/h4-8,10-11,13-14H,3,9H2,1-2H3,(H,17,18); Key:CLMFEXDZPBGYQQ-UHFFFAOYSA-N;

Fenestrel (INN, USAN) (developmental code name ORF-3858) is a synthetic, nonsteroidal estrogen that was developed as a postcoital contraceptive in the 1960s but was never marketed.^[1]^[2]^[3]^[4] Synthesized by Ortho Pharmaceutical in 1961 and studied extensively, it was coined the "morning-after-pill" or "postcoital antifertility agent".^[5] Fenestrel is a seco analogue of doisynolic acid, and a member of the cyclohexenecarboxylic acid series of estrogens.^[6]^[7]