Phenindione

Chemical compound From Wikipedia, the free encyclopedia

Phenindione is an anticoagulant which functions as a Vitamin K antagonist.

Pregnancy
category
Quick facts Clinical data, AHFS/Drugs.com ...
Phenindione
Clinical data
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
Routes of
administration
Oral
ATC code
Pharmacokinetic data
Protein binding88%
Elimination half-life5 to 10 hours
Identifiers
  • 2-phenyl-1H-indene-1,3(2H)-dione
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.001.323 Edit this at Wikidata
Chemical and physical data
FormulaC15H10O2
Molar mass222.243 g·mol−1
3D model (JSmol)
  • O=C2c1ccccc1C(=O)C2c3ccccc3
  • InChI=1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H checkY
  • Key:NFBAXHOPROOJAW-UHFFFAOYSA-N checkY
  (verify)
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Phenindione was introduced in the early 1950s. It acts similar to warfarin, but it has been associated with hypersensitivity reactions, so it is rarely used and warfarin is preferred.[1][2]

References

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