Fluorobenzaldehyde
Group of chemical compounds
From Wikipedia, the free encyclopedia
Fluorobenzaldehyde is a group of three constitutional isomers of fluorinated benzaldehyde.
Properties
The isomers differ in the location of the fluorine, but they have the same chemical formulas.
| Fluorobenzaldehyde isomers | |||
|---|---|---|---|
| Name | o-Fluorobenzaldehyde | m-Fluorobenzaldehyde | p-Fluorobenzaldehyde |
| Structure |  |
 |
 |
| Systematic name | 2-Fluorobenzaldehyde | 3-Fluorobenzaldehyde | 4-Fluorobenzaldehyde |
| Molecular formula | C7H5FO | C7H5FO | C7H5FO |
| Molar mass | 124.11 g/mol | 124.11 g/mol | 124.11 g/mol |
| CAS number | 446-52-6 | 456-48-4 | 459-57-4 |
| EC number | 207-171-2 | 207-266-9 | 459-57-4 |
| Properties | |||
| Melting point | −44.5 °C | −10 °C | |
| Boiling point | 175 °C | 173 °C | 181 °C |
| Flash point | 55 °C | 56 °C | 56 °C |
| Density | 1.18 g/cm3 | 1.174 g/cm3 | 1.175 g/cm3 |
Preparation
The 4-fluorobenzaldehyde isomer can be produced by a halogen-exchange reaction with 4-chlorobenzaldehyde.[1]
Uses
Fluorobenzaldehyde can be used as a synthetic intermediate because the fluorine can be replaced via oxidation reaction.[1] Due to the aldehyde group, the fluorobenzaldehydes can be used to make a variety of schiff base compounds through a condensation reaction, some of which have antimicrobial properties.[2][3]
