GDF1

GDF1
Identifiers
Aliases	GDF1, DORV, DTGA3, RAI, growth differentiation factor 1, CHTD6, UOG1, LASS1, CERS1, LAG1
External IDs	OMIM: 602880; MGI: 95683; HomoloGene: 105644; GeneCards: GDF1; OMA:GDF1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	18,896,158 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	70,784,237 bp
RNA expression pattern
	Top expressed in
	primary visual cortex; ; sural nerve; ; superior frontal gyrus; ; ganglionic eminence; ; skeletal muscle tissue; ; prefrontal cortex; ; muscle of thigh; ; sensory nervous system; ; sensory organ; ; face;
	Top expressed in
	striatum of neuraxis; ; epiblast; ; embryo; ; embryo; ; superior frontal gyrus; ; lateral plate mesoderm; ; embryonic organizer; ; adrenal gland; ; notochord; ; cerebellar cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	transforming growth factor beta receptor binding; cytokine activity; growth factor activity;
Cellular component	extracellular region; extracellular space;
Biological process	regulation of apoptotic process; positive regulation of pathway-restricted SMAD protein phosphorylation; regulation of MAPK cascade; SMAD protein signal transduction; cell development; BMP signaling pathway; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	2657
	14559
	ENSG00000130283
	ENSMUSG00000109523
	P27539
	P20863
	NM_001492; NM_001387438
	NM_001163282; NM_008107
	NP_001483
	NP_001156754; NP_032133
	Wikidata
View/Edit Human	View/Edit Mouse

Growth differentiation factor 1 (GDF1) is a protein that in humans is encoded by the GDF1 gene.^[5]

AliasesGDF1, DORV, DTGA3, RAI, growth differentiation factor 1, CHTD6, UOG1, LASS1, CERS1, LAG1

End18,896,158 bp^[1]

Quick facts Identifiers, Aliases ...

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GDF1 belongs to the transforming growth factor beta superfamily that has a role in left-right patterning and mesoderm induction during embryonic development.^[6] It is found in the brain, spinal cord and peripheral nerves of embryos.^[5]^[6]

References