Gem-associated protein 5

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Gem-associated protein 5 is a protein that in humans is encoded by the GEMIN5 gene.[5][6]

AliasesGEMIN5, GEMIN-5, gem nuclear organelle associated protein 5, NEDCAM
End154,938,211 bp[1]
Quick facts GEMIN5, Identifiers ...
GEMIN5
Identifiers
AliasesGEMIN5, GEMIN-5, gem nuclear organelle associated protein 5, NEDCAM
External IDsOMIM: 607005; MGI: 2449311; HomoloGene: 9155; GeneCards: GEMIN5; OMA:GEMIN5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015465
NM_001252156

NM_001166669
NM_001166670
NM_001166671
NM_172558
NM_001374702

RefSeq (protein)

NP_001239085
NP_056280

NP_001160141
NP_001160142
NP_001160143
NP_766146
NP_001361631

Location (UCSC)Chr 5: 154.89 – 154.94 MbChr 11: 58.01 – 58.06 Mb
PubMed search[3][4]
Wikidata
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Function

Gem-associated protein 5 is part of the SMN a large protein complex localized to both the cytoplasm and the nucleus that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), gem-associated protein 2 (SIP1; MIM 602595), GEMIN3 (DDX20; MIM 606168), and GEMIN4 (MIM 606969).[6]

Interactions

GEMIN5 has been shown to interact with DDX20[5][7] and SMN1.[5]

References

Further reading

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