GIMAP4

GTPase IMAP family member 4 is an enzyme that in humans is encoded by the GIMAP4 gene.^[4][5][6]

PDBOrtholog search: PDBe RCSB

AliasesGIMAP4, IAN-1, IAN1, IMAP4, MSTP062, GTPase, IMAP family member 4

External IDsOMIM: 608087; MGI: 1349656; HomoloGene: 75084; GeneCards: GIMAP4; OMA:GIMAP4 - orthologs

Chr.Chromosome 6 (mouse)^[1]

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GIMAP4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3LXX
Identifiers
Aliases	GIMAP4, IAN-1, IAN1, IMAP4, MSTP062, GTPase, IMAP family member 4
External IDs	OMIM: 608087; MGI: 1349656; HomoloGene: 75084; GeneCards: GIMAP4; OMA:GIMAP4 - orthologs
Gene location (Mouse) Chr. Chromosome 6 (mouse)[1] Band 6|6 B2.3 Start 48,661,483 bp[1] End 48,668,994 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte blood right lung lymph node spleen appendix superficial temporal artery pericardium Achilles tendon lower lobe of lung Top expressed in mesenteric lymph nodes spleen right lung lobe left lung left lung lobe renal corpuscle blood thymus carotid body subcutaneous adipose tissue More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 55303 107526 Ensembl n/a ENSMUSG00000054435 UniProt Q9NUV9 Q99JY3 RefSeq (mRNA) NM_018326 NM_001363532 NM_001243199 NM_001243200 NM_001243201 NM_174990 NM_175048 RefSeq (protein) NP_060796 NP_001350461 NP_001230128 NP_001230129 NP_001230130 NP_778155 NP_778213 Location (UCSC) n/a Chr 6: 48.66 – 48.67 Mb PubMed search [2] [3]
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This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The encoded protein of this gene may be negatively regulated by T-cell acute lymphocytic leukemia 1 (TAL1). In humans, the IAN subfamily genes are located in a cluster at 7q36.1.^[6]