GLUD2

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Glutamate dehydrogenase 2, mitochondrial, also known as GDH 2, is an enzyme that in humans is encoded by the GLUD2 gene.[3][4][5] This dehydrogenase is one of the family of glutamate dehydrogenases that are ubiquitous in life.

AliasesGLUD2, GDH2, GLUDP1, glutamate dehydrogenase 2
End121,050,094 bp[1]
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Function

Glutamate dehydrogenase 2 is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate.[3]

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