GPR110

Probable G-protein coupled receptor 110 is a protein that in humans is encoded by the GPR110 gene.^[5][6] This gene encodes a member of the adhesion-GPCR receptor family.^[7] Family members are characterized by an extended extracellular region with a variable number of N-terminal protein modules coupled to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.^[8]

AliasesADGRF1, KPG_012, PGR19, hGPCR36, GPR110, adhesion G protein-coupled receptor F1

External IDsOMIM: 617430; MGI: 1924846; HomoloGene: 124643; GeneCards: ADGRF1; OMA:ADGRF1 - orthologs

Chr.Chromosome 6 (human)^[1]

End47,042,350 bp^[1]

Quick facts ADGRF1, Identifiers ...

ADGRF1
Identifiers
Aliases	ADGRF1, KPG_012, PGR19, hGPCR36, GPR110, adhesion G protein-coupled receptor F1
External IDs	OMIM: 617430; MGI: 1924846; HomoloGene: 124643; GeneCards: ADGRF1; OMA:ADGRF1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p12.3|6 Start 46,997,708 bp[1] End 47,042,350 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 B3 Start 43,581,220 bp[2] End 43,635,628 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in palpebral conjunctiva amniotic fluid epithelium of nasopharynx olfactory zone of nasal mucosa buccal mucosa cell bronchial epithelial cell renal medulla right lobe of thyroid gland gallbladder oral cavity Top expressed in conjunctival fornix cornea right kidney liver duodenum human kidney colon renal cortex muscle of thigh hypothalamus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane extracellular region plasma membrane membrane intracellular anatomical structure Biological process G protein-coupled receptor signaling pathway cell surface receptor signaling pathway signal transduction synapse assembly memory neuron projection development positive regulation of CREB transcription factor activity adenylate cyclase-activating G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 266977 77596 Ensembl ENSG00000153292 ENSMUSG00000041293 UniProt Q5T601 Q8VEC3 RefSeq (mRNA) NM_025048 NM_153840 NM_133776 RefSeq (protein) NP_079324 NP_722582 NP_598537 Location (UCSC) Chr 6: 47 – 47.04 Mb Chr 17: 43.58 – 43.64 Mb PubMed search [3] [4]
Wikidata
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