GPR61

Probable G-protein coupled receptor 61 is a protein that in humans is encoded by the GPR61 gene.^[5][6][7]

AliasesGPR61, BALGR, GPCR3, G protein-coupled receptor 61

External IDsOMIM: 606916; MGI: 2441719; HomoloGene: 12910; GeneCards: GPR61; OMA:GPR61 - orthologs

Chr.Chromosome 1 (human)^[1]

End109,548,406 bp^[1]

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GPR61
Identifiers
Aliases	GPR61, BALGR, GPCR3, G protein-coupled receptor 61
External IDs	OMIM: 606916; MGI: 2441719; HomoloGene: 12910; GeneCards: GPR61; OMA:GPR61 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p13.3 Start 109,539,872 bp[1] End 109,548,406 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F2.3 Start 108,055,637 bp[2] End 108,062,198 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex right frontal lobe Brodmann area 9 testicle anterior pituitary right hemisphere of cerebellum cingulate gyrus anterior cingulate cortex hypothalamus nucleus accumbens Top expressed in medial dorsal nucleus medial geniculate nucleus ventromedial nucleus piriform cortex inferior colliculi lateral geniculate nucleus central gray substance of midbrain anterior amygdaloid area paraventricular nucleus of hypothalamus medial vestibular nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity protein binding arrestin family protein binding Cellular component integral component of membrane receptor complex membrane plasma membrane endosome endosome membrane Biological process signal transduction G protein-coupled receptor signaling pathway positive regulation of cAMP-mediated signaling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 83873 229714 Ensembl ENSG00000156097 ENSMUSG00000046793 UniProt Q9BZJ8 Q8C010 RefSeq (mRNA) NM_031936 NM_001393907 NM_175470 NM_001305461 RefSeq (protein) NP_114142 NP_001292390 Location (UCSC) Chr 1: 109.54 – 109.55 Mb Chr 3: 108.06 – 108.06 Mb PubMed search [3] [4]
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This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors.^[7]