GPR62

Probable G-protein coupled receptor 62 is a protein that in humans is encoded by the GPR62 gene.^[5][6]

AliasesGPR62, GPCR8, KPG_005, G protein-coupled receptor 62

External IDsOMIM: 606917; MGI: 3525078; HomoloGene: 50962; GeneCards: GPR62; OMA:GPR62 - orthologs

Chr.Chromosome 3 (human)^[1]

End51,957,499 bp^[1]

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GPR62
Identifiers
Aliases	GPR62, GPCR8, KPG_005, G protein-coupled receptor 62
External IDs	OMIM: 606917; MGI: 3525078; HomoloGene: 50962; GeneCards: GPR62; OMA:GPR62 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p21.2 Start 51,955,381 bp[1] End 51,957,499 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 F1 Start 106,341,161 bp[2] End 106,343,137 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in inferior ganglion of vagus nerve C1 segment internal globus pallidus subthalamic nucleus endothelial cell ventral tegmental area corpus callosum substantia nigra external globus pallidus medulla oblongata Top expressed in lumbar subsegment of spinal cord seminiferous tubule deep cerebellar nuclei substantia nigra anterior horn of spinal cord suprachiasmatic nucleus pontine nuclei lateral geniculate nucleus spermatocyte ventral tegmental area More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity protein binding identical protein binding arrestin family protein binding Cellular component integral component of membrane receptor complex membrane plasma membrane endosome endosome membrane Biological process signal transduction G protein-coupled receptor signaling pathway positive regulation of cAMP-mediated signaling inositol phosphate-mediated signaling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 118442 436090 Ensembl ENSG00000180929 ENSMUSG00000091735 UniProt Q9BZJ7 Q80UC6 RefSeq (mRNA) NM_080865 NM_001159652 RefSeq (protein) NP_543141 NP_001153124 Location (UCSC) Chr 3: 51.96 – 51.96 Mb Chr 9: 106.34 – 106.34 Mb PubMed search [3] [4]
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G protein–coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM]^[6]