GPRC6A

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

G protein-coupled receptor family C group 6 member A (GPRC6A) is a protein that in humans is encoded by the GPRC6A gene.[5] This protein functions as a receptor of L-α-amino acids,[6] cations (e.g., calcium),[7] osteocalcin,[8] and steroids.[9] It is a membrane androgen receptor.

AliasesGPRC6A, GPCR, bA86F4.3, G protein-coupled receptor class C group 6 member A
End116,829,083 bp[1]
Quick facts Identifiers, Aliases ...
GPRC6A
Identifiers
AliasesGPRC6A, GPCR, bA86F4.3, G protein-coupled receptor class C group 6 member A
External IDsOMIM: 613572; MGI: 2429498; HomoloGene: 17529; GeneCards: GPRC6A; OMA:GPRC6A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_148963
NM_001286354
NM_001286355

NM_153071

RefSeq (protein)

NP_001273283
NP_001273284
NP_683766

NP_694711

Location (UCSC)Chr 6: 116.79 – 116.83 MbChr 10: 51.49 – 51.51 Mb
PubMed search[3][4]
Wikidata
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Clinical significance

GPRC6A has also been linked to prostate cancer progression, and it has been shown to mediate rapid, non-genomic prostate cancer cell responses to testosterone.[10]

See also

References

Further reading

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