GPRC6A

GPRC6A
Identifiers
Aliases	GPRC6A, GPCR, bA86F4.3, G protein-coupled receptor class C group 6 member A
External IDs	OMIM: 613572; MGI: 2429498; GeneCards: GPRC6A
Gene location (Human)
Chr.	Chromosome 6 (human)
End	116,829,083 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	51,507,557 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; salivary gland; ; minor salivary glands; ; islet of Langerhans; ; human kidney; ; right adrenal gland; ; right adrenal cortex; ; muscle of thigh; ; left adrenal gland;
	Top expressed in
	embryo; ; embryo; ; left lung lobe; ; right lung lobe; ; islet of Langerhans;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; signaling receptor activity;
Cellular component	integral component of membrane; cell surface; plasma membrane; intracellular anatomical structure; membrane; integral component of plasma membrane;
Biological process	response to amino acid; calcium-mediated signaling; signal transduction; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	222545
	210198
	ENSG00000173612
	ENSMUSG00000019905
	Q5T6X5
	Q8K4Z6
	NM_148963; NM_001286354; NM_001286355
	NM_153071
	NP_001273283; NP_001273284; NP_683766
	NP_694711
	Wikidata
View/Edit Human	View/Edit Mouse

G protein-coupled receptor family C group 6 member A (GPRC6A) is a protein that in humans is encoded by the GPRC6A gene.^[5] This protein functions as a receptor of L-α-amino acids,^[6] cations (e.g., calcium),^[7] and osteocalcin.^[8] It has also been found to mediate some of the effects of testosterone, but the direct affinity with the receptor is relative low, so the precise mechanism remains controversial.^[9]