GPSM2

GPSM2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3SF4, 4WNE, 4WNF, 4WNG, 5A6C
Identifiers
Aliases	GPSM2, CMCS, DFNB82, LGN, PINS, G-protein signaling modulator 2, G protein signaling modulator 2
External IDs	OMIM: 609245; MGI: 1923373; HomoloGene: 56584; GeneCards: GPSM2; OMA:GPSM2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	108,934,545 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	108,629,625 bp
RNA expression pattern
	Top expressed in
	tibia; ; buccal mucosa cell; ; amniotic fluid; ; tendon of biceps brachii; ; ventricular zone; ; endothelial cell; ; corpus callosum; ; Achilles tendon; ; internal globus pallidus; ; inferior ganglion of vagus nerve;
	Top expressed in
	neural layer of retina; ; retinal pigment epithelium; ; genital tubercle; ; ventricular zone; ; tail of embryo; ; hair follicle; ; Paneth cell; ; photoreceptor layer of retina; ; tunica media of zone of aorta; ; condyle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	G-protein alpha-subunit binding; nucleotide binding; protein binding; GTPase regulator activity; identical protein binding; GDP-dissociation inhibitor activity; dynein complex binding; protein C-terminus binding; protein domain specific binding; protein self-association;
Cellular component	mitotic spindle pole; spindle pole; cytoskeleton; cytosol; cytoplasm; cell cortex region; cell cortex; lateral cell cortex; plasma membrane; membrane; lateral plasma membrane; centrosome; protein-containing complex;
Biological process	mitotic spindle organization; G protein-coupled receptor signaling pathway; maintenance of centrosome location; regulation of catalytic activity; Ran protein signal transduction; regulation of mitotic spindle organization; positive regulation of protein localization to cell cortex; positive regulation of spindle assembly; cell cycle; cell division; establishment of mitotic spindle orientation;
	Sources:Amigo / QuickGO
Orthologs
	29899
	76123
	ENSG00000121957
	ENSMUSG00000027883
	P81274
	Q8VDU0
	NM_013296; NM_001321038; NM_001321039
	NM_029522
NP_001307967; NP_001307968; NP_037428; NP_037428.3; NP_001307967.1;
	NP_001307968.1
	NP_083798
	Wikidata
View/Edit Human	View/Edit Mouse

G-protein-signaling modulator 2, also called LGN for its 10 Leucine-Glycine-Asparagine repeats, is a protein that in humans is encoded by the GPSM2 gene.^[5]^[6]^[7]