GREB1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Growth regulation by estrogen in breast cancer 1 is a protein that in humans is encoded by the GREB1 gene.[5]

AliasesGREB1, growth regulation by estrogen in breast cancer 1, growth regulating estrogen receptor binding 1
End11,642,788 bp[1]
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GREB1
Identifiers
AliasesGREB1, growth regulation by estrogen in breast cancer 1, growth regulating estrogen receptor binding 1
External IDsOMIM: 611736; MGI: 2149712; HomoloGene: 8780; GeneCards: GREB1; OMA:GREB1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014668
NM_033090
NM_148903

NM_001252071
NM_015764

RefSeq (protein)

NP_055483
NP_149081
NP_683701

NP_001239000
NP_056579

Location (UCSC)Chr 2: 11.48 – 11.64 MbChr 12: 16.72 – 16.85 Mb
PubMed search[3][4]
Wikidata
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Function

This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[5]

References

Further reading

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