H2BFWT

H2BW1
Identifiers
Aliases	H2BW1, H2B histone family member W, testis specific, H2BFWT, H2B.W histone 1, TH2B-175
External IDs	OMIM: 300507; HomoloGene: 128214; GeneCards: H2BW1; OMA:H2BW1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	104,013,708 bp
RNA expression pattern
	Top expressed in
	testicle; ; right testis; ; placenta; ; left testis; ; right coronary artery; ; prefrontal cortex; ; tonsil; ; superior frontal gyrus; ; blood;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; protein heterodimerization activity;
Cellular component	nucleosome; nuclear membrane; membrane; nucleus; chromosome;
Biological process	nucleosome assembly;
	Sources:Amigo / QuickGO
Orthologs
	158983
	n/a
	ENSG00000123569
	n/a
	Q7Z2G1
	n/a
	NM_001002916
	n/a
	NP_001002916
	n/a
	Wikidata
View/Edit Human

H2B histone family, member W, testis-specific is a protein that in humans is encoded by the H2BFWT gene.^[3]

AliasesH2BW1, H2B histone family member W, testis specific, H2BFWT, H2B.W histone 1, TH2B-175

External IDsOMIM: 300507; HomoloGene: 128214; GeneCards: H2BW1; OMA:H2BW1 - orthologs

Chr.X chromosome (human)^[1]

End104,013,708 bp^[1]

Quick facts H2BW1, Identifiers ...

Close

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.[provided by RefSeq, Jan 2010].^[3]

[3]

[1]

[2]

H2BFWT

References

Further reading

Related Articles