HDHD1A

PUDP
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3L5K
Identifiers
Aliases	PUDP, DXF68S1E, FAM16AX, GS1, HDHD1A, HDHD1, pseudouridine 5'-phosphatase
External IDs	OMIM: 306480; MGI: 1914615; HomoloGene: 8093; GeneCards: PUDP; OMA:PUDP - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	7,148,158 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	50,734,491 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of rectus abdominis; ; gonad; ; mucosa of sigmoid colon; ; biceps brachii; ; secondary oocyte; ; deltoid muscle; ; Skeletal muscle tissue of biceps brachii; ; tibialis anterior muscle; ; epithelium of bronchus; ; bronchial epithelial cell;
	Top expressed in
	seminiferous tubule; ; spermatid; ; spermatocyte; ; zygote; ; secondary oocyte; ; primary oocyte; ; islet of Langerhans;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	pseudouridine 5'-phosphatase activity; hydrolase activity; metal ion binding; phosphatase activity; molecular function; magnesium ion binding;
Cellular component	cytosol; cytoplasm;
Biological process	pyrimidine nucleoside salvage; metabolism; nucleotide metabolic process; dephosphorylation; biological process;
	Sources:Amigo / QuickGO
Orthologs
	8226
	67365
	ENSG00000130021
	ENSMUSG00000048875
	Q08623
	Q9D5U5
	NM_012080; NM_001135565; NM_001178135; NM_001178136
	NM_026108
	NP_001129037; NP_001171606; NP_001171607; NP_036212
	NP_080384
	Wikidata
View/Edit Human	View/Edit Mouse

Haloacid dehalogenase-like hydrolase domain-containing protein 1A is an enzyme that in humans is encoded by the HDHD1A gene.^[5]^[6]^[7] It encodes a pseudouridine-5'-phosphatase but can also accommodate other phopshorylated metabolites with a lower affinity.^[8]^[9]