HHAT

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Hedgehog acyltransferase (HHAT), also called skinny hedgehog homology in humans, is a human gene.[1][2]

SymbolHHAT
Alt. symbolsFLJ10724, MART-2, MART2, GUP2
Quick facts hedgehog acyltransferase, Identifiers ...
hedgehog acyltransferase
Identifiers
SymbolHHAT
Alt. symbolsFLJ10724, MART-2, MART2, GUP2
NCBI gene55733
HGNC18270
OMIM605743
RefSeqNM_018194
UniProtQ5VTY9
Other data
EC number2.3.1.-
LocusChr. 1 q32
Search for
StructuresSwiss-model
DomainsInterPro
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The HHAT gene encodes an enzyme that catalyzes N-terminal palmitoylation of sonic hedgehog. Mutations in HHAT produce a phenotype that is similar to loss of hedgehog function. Finally the HHAT protein shares a short but significant sequence similarity to membrane-bound O-acyltransferases.[3]

References

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