HNRNPLL

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Heterogeneous nuclear ribonucleoprotein L-like is a protein that in humans is encoded by the HNRNPLL gene.[5]

PDBOrtholog search: PDBe RCSB
AliasesHNRNPLL, HNRPLL, SRRF, heterogeneous nuclear ribonucleoprotein L like
Quick facts Available structures, PDB ...
HNRNPLL
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesHNRNPLL, HNRPLL, SRRF, heterogeneous nuclear ribonucleoprotein L like
External IDsOMIM: 611208; MGI: 1919942; HomoloGene: 26701; GeneCards: HNRNPLL; OMA:HNRNPLL - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001142650
NM_138394

NM_144802

RefSeq (protein)

NP_001136122
NP_612403

NP_659051

Location (UCSC)Chr 2: 38.56 – 38.6 MbChr 17: 80.34 – 80.37 Mb
PubMed search[3][4]
Wikidata
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Function

HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation.[6]

References

Further reading

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