HOXB1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Homeobox protein Hox-B1 is a protein that in humans is encoded by the HOXB1 gene.[5][6][7]

PDBOrtholog search: PDBe RCSB
AliasesHOXB1, HCFP3, HOX2, HOX2I, Hox-2.9, homeobox B1
Quick facts Available structures, PDB ...
HOXB1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesHOXB1, HCFP3, HOX2, HOX2I, Hox-2.9, homeobox B1
External IDsOMIM: 142968; MGI: 96182; HomoloGene: 1615; GeneCards: HOXB1; OMA:HOXB1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002144

NM_008266

RefSeq (protein)

NP_002135

NP_032292

Location (UCSC)Chr 17: 48.53 – 48.53 MbChr 11: 96.26 – 96.26 Mb
PubMed search[3][4]
Wikidata
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Function

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.[7]

Interactions

HOXB1 has been shown to interact with PBX1.[8][9]

See also

References

Further reading

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