HOXB2
Protein-coding gene in humans
From Wikipedia, the free encyclopedia
Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene.[5][6][7]
External IDsOMIM: 142967; MGI: 96183; HomoloGene: 37584; GeneCards: HOXB2; OMA:HOXB2 - orthologs
Function
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer.[7]