HOXB2

Protein-coding gene in humans From Wikipedia, the free encyclopedia

Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene.[5][6][7]

AliasesHOXB2, HOX2, HOX2H, Hox-2.8, K8, homeobox B2
End48,545,109 bp[1]
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HOXB2
Identifiers
AliasesHOXB2, HOX2, HOX2H, Hox-2.8, K8, homeobox B2
External IDsOMIM: 142967; MGI: 96183; HomoloGene: 37584; GeneCards: HOXB2; OMA:HOXB2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002145

NM_134032

RefSeq (protein)

NP_002136

NP_598793

Location (UCSC)Chr 17: 48.54 – 48.55 MbChr 11: 96.24 – 96.24 Mb
PubMed search[3][4]
Wikidata
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Function

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer.[7]

See also

References

Further reading

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