HOXB9
Protein-coding gene in humans
From Wikipedia, the free encyclopedia
Homeobox protein Hox-B9 is a protein that in humans is encoded by the HOXB9 gene.[5][6][7]
External IDsOMIM: 142964; MGI: 96190; HomoloGene: 7367; GeneCards: HOXB9; OMA:HOXB9 - orthologs
Function
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.[7]