HOXC12

Homeobox C12 is a protein that in humans is encoded by the HOXC12 gene.^[5]

AliasesHOXC12, HOC3F, HOX3, HOX3F, homeobox C12

External IDsOMIM: 142975; MGI: 96194; HomoloGene: 7769; GeneCards: HOXC12; OMA:HOXC12 - orthologs

Chr.Chromosome 12 (human)^[1]

End53,958,956 bp^[1]

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HOXC12
Identifiers
Aliases	HOXC12, HOC3F, HOX3, HOX3F, homeobox C12
External IDs	OMIM: 142975; MGI: 96194; HomoloGene: 7769; GeneCards: HOXC12; OMA:HOXC12 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.13 Start 53,954,903 bp[1] End 53,958,956 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15 F3|15 58.01 cM Start 102,845,192 bp[2] End 102,847,044 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle skin of leg sural nerve popliteal artery tibial arteries skin of abdomen subcutaneous adipose tissue olfactory zone of nasal mucosa mammary gland female breast Top expressed in tail of embryo genital tubercle neural tube hair follicle mesenchyme skeleton leg More reference expression data BioGPS n/a
Gene ontology Molecular function sequence-specific DNA binding DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus Biological process multicellular organism development regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3228 15421 Ensembl ENSG00000123407 ENSMUSG00000050328 UniProt P31275 Q8K5B8 RefSeq (mRNA) NM_173860 NM_010463 RefSeq (protein) NP_776272 NP_034593 Location (UCSC) Chr 12: 53.95 – 53.96 Mb Chr 15: 102.85 – 102.85 Mb PubMed search [3] [4]
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This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12.^[5]