HSF2
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Heat shock factor protein 2 is a protein that in humans is encoded by the HSF2 gene.[5][6]
External IDsOMIM: 140581; MGI: 96239; HomoloGene: 37931; GeneCards: HSF2; OMA:HSF2 - orthologs
Function
HSF2, as well as the related gene HSF1, encodes a protein that binds specifically to the heat-shock element and has homology to HSFs of other species. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Although the names HSF1 and HSF2 were chosen for historical reasons, these peptides should be referred to as heat-shock transcription factors.[6]
Interactions
HSF2 has been shown to interact with Nucleoporin 62[7] and HSF1.[8]
