IFT80

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Intraflagellar transport protein 80 homolog (IFT80), also known as WD repeat-containing protein 56, is a protein that in humans is encoded by the IFT80 gene.[5][6]

AliasesIFT80, ATD2, SRTD2, WDR56, intraflagellar transport 80, FAP167
End160,399,880 bp[1]
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IFT80
Identifiers
AliasesIFT80, ATD2, SRTD2, WDR56, intraflagellar transport 80, FAP167
External IDsOMIM: 611177; MGI: 1915509; HomoloGene: 12253; GeneCards: IFT80; OMA:IFT80 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020800
NM_001190241
NM_001190242

NM_026641

RefSeq (protein)

NP_001177170
NP_001177171
NP_065851

NP_080917

Location (UCSC)Chr 3: 160.26 – 160.4 MbChr 3: 68.8 – 68.91 Mb
PubMed search[3][4]
Wikidata
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Function

IFT80 is part of the intraflagellar transport complex B and is necessary for the function of motile and sensory cilia.[5]

Clinical significance

Mutations in the IFT80 gene are associated with asphyxiating thoracic dysplasia.[6]

References

Further reading

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