IL22RA1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Interleukin 22 receptor, alpha 1 is a protein that in humans is encoded by the IL22RA1 gene.[5]

PDBOrtholog search: PDBe RCSB
AliasesIL22RA1, CRF2-9, IL22R, IL22R1, interleukin 22 receptor subunit alpha 1
Quick facts Available structures, PDB ...
IL22RA1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesIL22RA1, CRF2-9, IL22R, IL22R1, interleukin 22 receptor subunit alpha 1
External IDsOMIM: 605457; MGI: 2663588; HomoloGene: 10943; GeneCards: IL22RA1; OMA:IL22RA1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021258

NM_178257

RefSeq (protein)

NP_067081

NP_839988

Location (UCSC)Chr 1: 24.12 – 24.14 MbChr 4: 135.46 – 135.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10RB/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36.

References

Further reading

Related Articles

Wikiwand AI