IL36A

IL36A
Identifiers
Aliases	IL36A, FIL1, FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON), IL1F6, interleukin 36, alpha, interleukin 36 alpha
External IDs	OMIM: 605509; MGI: 1859324; HomoloGene: 8688; GeneCards: IL36A; OMA:IL36A - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	113,008,044 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	24,115,714 bp
RNA expression pattern
	Top expressed in
	epithelium of esophagus; ; testicle; ; oral cavity; ; mucosa of pharynx; ; body of tongue; ; pancreatic ductal cell; ; buccal mucosa cell; ; gums; ; tonsil; ; vagina;
	Top expressed in
	esophagus; ; lip; ; cervix; ; right ventricle; ; skin of external ear; ; umbilical cord; ; tibiofemoral joint; ; lumbar subsegment of spinal cord; ; temporal muscle; ; digastric muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	interleukin-1 receptor binding; cytokine activity;
Cellular component	extracellular region; extracellular space;
Biological process	positive regulation of interleukin-6 production; innate immune response; positive regulation of cytokine production; immune system process; inflammatory response; immune response; regulation of signaling receptor activity; cytokine-mediated signaling pathway; neutrophil chemotaxis; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of JNK cascade; cellular response to lipopolysaccharide;
	Sources:Amigo / QuickGO
Orthologs
	27179
	54448
	ENSG00000136694
	ENSMUSG00000026984
	Q9UHA7
	Q9JLA2
	NM_014440
	NM_019450
	NP_055255
	NP_062323
	Wikidata
View/Edit Human	View/Edit Mouse

Interleukin-36 alpha also known as interleukin-1 family member 6 (IL1F6) is a protein that in humans is encoded by the IL36A gene.^[5]^[6]