IL36B

IL36B
Identifiers
Aliases	IL36B, FIL1, FIL1-(ETA), FIL1H, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, interleukin 36, beta, interleukin 36 beta
External IDs	OMIM: 605508; MGI: 1916927; HomoloGene: 18278; GeneCards: IL36B; OMA:IL36B - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	113,052,867 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	24,050,531 bp
RNA expression pattern
	Top expressed in
	skin of leg; ; skin of abdomen; ; islet of Langerhans; ; tonsil; ; stromal cell of endometrium; ; vagina; ; head; ; mouth; ; exocrine gland; ; oral mucosa;
	Top expressed in
	esophagus; ; lip; ; skin of external ear; ; cervix; ; umbilical cord; ; lumbar subsegment of spinal cord; ; trachea; ; granulocyte; ; skin of abdomen; ; digastric muscle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	cytokine activity; interleukin-1 receptor binding;
Cellular component	extracellular region; extracellular space;
Biological process	innate immune response; inflammatory response; immune response; immune system process; regulation of signaling receptor activity; cytokine-mediated signaling pathway; neutrophil chemotaxis; positive regulation of interleukin-6 production; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of T cell differentiation; positive regulation of JNK cascade; cellular response to lipopolysaccharide;
	Sources:Amigo / QuickGO
Orthologs
	27177
	69677
	ENSG00000136696
	ENSMUSG00000026985
	Q9NZH7
	Q9D6Z6
	NM_014438; NM_173178
	NM_027163
	NP_055253; NP_775270
	NP_081439
	Wikidata
View/Edit Human	View/Edit Mouse

Interleukin-36 beta also known as interleukin-1 family member 8 (IL1F8) is a protein that in humans is encoded by the IL36B gene.^[5]^[6]^[7]^[8]