IMPDH2

IMPDH2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1B3O, 1NF7, 1NFB
Identifiers
Aliases	IMPDH2, IMPD2, IMPDH-II, IMP (inosine 5'-monophosphate) dehydrogenase 2, inosine monophosphate dehydrogenase 2
External IDs	OMIM: 146691; MGI: 109367; HomoloGene: 48919; GeneCards: IMPDH2; OMA:IMPDH2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	49,029,447 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	108,442,783 bp
RNA expression pattern
	Top expressed in
	left ovary; ; body of pancreas; ; cartilage tissue; ; right ovary; ; right uterine tube; ; gingival epithelium; ; ventricular zone; ; canal of the cervix; ; skin of leg; ; vulva;
	Top expressed in
	morula; ; epiblast; ; uterus; ; ventricular zone; ; embryo; ; embryo; ; blastocyst; ; spermatid; ; yolk sac; ; ovary;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; metal ion binding; catalytic activity; protein binding; RNA binding; oxidoreductase activity; nucleotide binding; IMP dehydrogenase activity;
Cellular component	cytoplasm; membrane; peroxisomal membrane; extracellular exosome; nucleus; extracellular region; cytosol; secretory granule lumen; ficolin-1-rich granule lumen;
Biological process	cellular response to interleukin-4; purine nucleotide biosynthetic process; retina development in camera-type eye; purine ribonucleoside monophosphate biosynthetic process; lymphocyte proliferation; GMP biosynthetic process; protein homotetramerization; GTP biosynthetic process; neutrophil degranulation; circadian rhythm;
	Sources:Amigo / QuickGO
Orthologs
	3615
	23918
	ENSG00000178035
	ENSMUSG00000062867
	P12268
	P24547
	NM_000884
	NM_011830; NM_001378921
	NP_000875
	NP_035960; NP_001365850
	Wikidata
View/Edit Human	View/Edit Mouse

Inosine-5'-monophosphate dehydrogenase 2, also known as IMP dehydrogenase 2, is an enzyme that in humans is encoded by the IMPDH2 gene.^[5]^[6]^[7]