INSRR

INSRR
Identifiers
Aliases	INSRR, IRR, insulin receptor related receptor
External IDs	OMIM: 147671; MGI: 1346037; HomoloGene: 56539; GeneCards: INSRR; OMA:INSRR - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	156,859,117 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	87,723,408 bp
RNA expression pattern
	Top expressed in
	body of stomach; ; human kidney; ; body of uterus; ; right testis; ; apex of heart; ; myometrium; ; canal of the cervix; ; fundus; ; left testis; ; abdominal wall;
	Top expressed in
	islet of Langerhans; ; right kidney; ; cingulate gyrus; ; embryo; ; internal carotid artery; ; external carotid artery; ; central gray substance of midbrain; ; glossopharyngeal ganglion; ; nucleus of stria terminalis; ; human kidney;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transmembrane receptor protein tyrosine kinase activity; phosphatidylinositol 3-kinase binding; insulin receptor substrate binding; nucleotide binding; protein kinase activity; protein tyrosine kinase activity; transferase activity; ATP binding; kinase activity; receptor tyrosine kinase; transmembrane signaling receptor activity; insulin-activated receptor activity;
Cellular component	receptor complex; integral component of membrane; integral component of plasma membrane; membrane; cytoplasm; insulin receptor complex; axon;
Biological process	actin cytoskeleton reorganization; protein autophosphorylation; protein phosphorylation; cellular response to alkaline pH; male sex determination; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; peptidyl-tyrosine phosphorylation; insulin receptor signaling pathway; negative regulation of signal transduction; cell differentiation; glucose homeostasis; negative regulation of apoptotic process; positive regulation of ERK1 and ERK2 cascade; anatomical structure development;
	Sources:Amigo / QuickGO
Orthologs
	3645
	23920
	ENSG00000027644
	ENSMUSG00000005640
	P14616
	Q9WTL4
	NM_014215
	NM_011832
	NP_055030
	NP_035962
	Wikidata
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