IPALT
Pharmaceutical compound
From Wikipedia, the free encyclopedia
iPALT, or ALiPT, also known as N-isopropyl-N-allyltryptamine or by its developmental code name ASR-3003, is a serotonin receptor modulator of the tryptamine family.[1] It is an asymmetrical analogue of diisopropyltryptamine (DiPT) and diallyltryptamine (DALT).[1] The drug is a non-selective serotonin receptor agonist, including of the serotonin 5-HT1B, 5-HT2A, 5-HT2B, and 5-HT6 receptors, but not of the serotonin 5-HT1A receptor.[1] It is also a serotonin reuptake inhibitor, but does not inhibit dopamine or norepinephrine reuptake.[1] The drug shows rather low potency for many of these actions, with for example 47-fold lower potency as a serotonin 5-HT2A receptor agonist than the known psychedelic drug 5-MeO-iPALT (ASR-3001).[1] The chemical synthesis of iPALT has been described.[1] Derivatives of iPALT include 5-MeO-iPALT (ASR-3001), 4-HO-iPALT, and 2-Me-iPALT (ASR-3002).[1] 5-MeO-iPALT is known to be a psychedelic drug in humans and is under development for potential medical use.[2][3][4][5] iPALT was patented by the Alexander Shulgin Research Institute (ASRI) in 2024.[1]
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| Other names | ALiPT; ASR-3003; ASR3003; N-Isopropyl-N-allyltryptamine; N-Allyl-N-isopropyltryptamine |
| Drug class | Serotonin receptor modulator; Serotonin 5-HT2A receptor agonist |
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| Chemical and physical data | |
| Formula | C16H22N2 |
| Molar mass | 242.366 g·mol−1 |
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See also
- Substituted tryptamine
- Propylallyltryptamine (PALT; ASR-3004)