IRF2
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Interferon regulatory factor 2 is a protein that in humans is encoded by the IRF2 gene.[5]
External IDsOMIM: 147576; MGI: 96591; HomoloGene: 1659; GeneCards: IRF2; OMA:IRF2 - orthologs
Function
IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.[6]