KCNJ9

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

G protein-activated inward rectifier potassium channel 3 is a protein that in humans is encoded by the KCNJ9 gene.[5][6][7]

AliasesKCNJ9, GIRK3, KIR3.3, potassium voltage-gated channel subfamily J member 9, potassium inwardly rectifying channel subfamily J member 9
End160,090,563 bp[1]
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KCNJ9
Identifiers
AliasesKCNJ9, GIRK3, KIR3.3, potassium voltage-gated channel subfamily J member 9, potassium inwardly rectifying channel subfamily J member 9
External IDsOMIM: 600932; MGI: 108007; HomoloGene: 37989; GeneCards: KCNJ9; OMA:KCNJ9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004983

NM_008429
NM_001360808

RefSeq (protein)

NP_004974

NP_032455
NP_001347737

Location (UCSC)Chr 1: 160.08 – 160.09 MbChr 1: 172.15 – 172.16 Mb
PubMed search[3][4]
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Function

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex.[7]

Interactions

KCNJ9 has been shown to interact with KCNJ6.[8][9]

See also

References

Further reading

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