KCNK17

Potassium channel subfamily K member 17 is a protein that in humans is encoded by the KCNK17 gene.^[3][4]

AliasesKCNK17, K2p17.1, TALK-2, TALK2, TASK-4, TASK4, potassium two pore domain channel subfamily K member 17

External IDsOMIM: 607370; HomoloGene: 88928; GeneCards: KCNK17; OMA:KCNK17 - orthologs

Chr.Chromosome 6 (human)^[1]

End39,314,461 bp^[1]

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KCNK17
Identifiers
Aliases	KCNK17, K2p17.1, TALK-2, TALK2, TASK-4, TASK4, potassium two pore domain channel subfamily K member 17
External IDs	OMIM: 607370; HomoloGene: 88928; GeneCards: KCNK17; OMA:KCNK17 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p21.2 Start 39,299,001 bp[1] End 39,314,461 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ascending aorta Descending thoracic aorta right coronary artery islet of Langerhans left coronary artery right lung upper lobe of lung upper lobe of left lung lower lobe of lung tibia n/a More reference expression data BioGPS n/a
Gene ontology Molecular function voltage-gated ion channel activity potassium channel activity potassium ion leak channel activity Cellular component integral component of membrane plasma membrane membrane integral component of plasma membrane Biological process potassium ion transport regulation of ion transmembrane transport ion transport potassium ion transmembrane transport stabilization of membrane potential Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 89822 n/a Ensembl ENSG00000124780 n/a UniProt Q96T54 n/a RefSeq (mRNA) NM_001135111 NM_031460 n/a RefSeq (protein) NP_001128583 NP_113648 n/a Location (UCSC) Chr 6: 39.3 – 39.31 Mb n/a PubMed search [2] n/a
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This gene encodes K_2P17.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This open channel, primarily expressed in the pancreas, is activated at alkaline pH.^[4]