KIF14

KIF14
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4OZQ
Identifiers
Aliases	KIF14, MKS12, kinesin family member 14, MCPH20
External IDs	OMIM: 611279; MGI: 1098226; HomoloGene: 8916; GeneCards: KIF14; OMA:KIF14 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	200,620,751 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	136,459,249 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; trabecular bone; ; gonad; ; ventricular zone; ; buccal mucosa cell; ; testicle; ; embryo; ; bone marrow; ; thymus; ; ganglionic eminence;
	Top expressed in
	zygote; ; tail of embryo; ; genital tubercle; ; secondary oocyte; ; spermatocyte; ; ventricular zone; ; spermatid; ; yolk sac; ; blastocyst; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	tubulin binding; nucleotide binding; protein kinase binding; plus-end-directed microtubule motor activity; PDZ domain binding; microtubule motor activity; microtubule binding; ATP binding; protein binding; ATPase activity;
Cellular component	spindle; cytoplasm; kinesin complex; nucleus; membrane; midbody; microtubule; plasma membrane; spindle midzone; cytoskeleton; cytosol; Flemming body;
Biological process	negative regulation of integrin activation; cerebral cortex development; negative regulation of apoptotic process; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; regulation of neuron apoptotic process; hippocampus development; regulation of cell growth; cell division; substrate adhesion-dependent cell spreading; regulation of G1/S transition of mitotic cell cycle; cell proliferation in forebrain; regulation of G2/M transition of mitotic cell cycle; cerebellar granular layer structural organization; olfactory bulb development; microtubule depolymerization; proteasome-mediated ubiquitin-dependent protein catabolic process; cerebellar Purkinje cell layer structural organization; regulation of myelination; positive regulation of cell population proliferation; regulation of Rap protein signal transduction; cerebellar cortex development; positive regulation of cytokinesis; negative regulation of neuron apoptotic process; establishment of protein localization; regulation of cell migration; mitotic metaphase plate congression; regulation of cell maturation; microtubule-based movement; activation of protein kinase activity; regulation of cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	9928
	381293
	ENSG00000118193
	ENSMUSG00000041498
	Q15058
	L0N7N1
	NM_001305792; NM_014875
	NM_001081258; NM_001287179
	NP_001292721; NP_055690
	NP_001274108
	Wikidata
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