KIF4A
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Kinesin family member 4A is a protein that in humans is encoded by the KIF4A gene.[5][6]
External IDsOMIM: 300521; MGI: 108389; HomoloGene: 69022; GeneCards: KIF4A; OMA:KIF4A - orthologs
| KIF4A | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | KIF4A, KIF4, KIF4G1, MRX100, kinesin family member 4A, XLID100 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 300521; MGI: 108389; HomoloGene: 69022; GeneCards: KIF4A; OMA:KIF4A - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Function
Kinesins, such as KIF4A, are microtubule-based motor proteins that generate directional movement along microtubules. They are involved in many crucial cellular processes, including cell division.[6]
Interactions
Clinical significance
NTCP is the entry receptor for both Hepatitis B (HBV) and Hepatitis D viruses (HDV).[9] KIF4 was found to play an essential role in HBV and HDV infection through its regulation of the retrograde transport of NTCP from the cytoplasm to the cell surface where it acts as a receptor for HBV/HDV infection.[10]