KIF5C

Kinesin heavy chain isoform 5C is a protein that in humans is encoded by the KIF5C gene.^[5][6] It is part of the kinesin family of motor proteins.

PDBOrtholog search: PDBe RCSB

AliasesKIF5C, CDCBM2, KINN, NKHC, NKHC-2, NKHC2, kinesin family member 5C

External IDsOMIM: 604593; MGI: 1098269; HomoloGene: 56234; GeneCards: KIF5C; OMA:KIF5C - orthologs

Chr.Chromosome 2 (human)^[1]

Quick facts Available structures, PDB ...

KIF5C
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1VFV, 1VFW, 1VFX, 1VFZ, 3J6H, 3WRD, 3X2T
Identifiers
Aliases	KIF5C, CDCBM2, KINN, NKHC, NKHC-2, NKHC2, kinesin family member 5C
External IDs	OMIM: 604593; MGI: 1098269; HomoloGene: 56234; GeneCards: KIF5C; OMA:KIF5C - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q23.1-q23.2 Start 148,875,227 bp[1] End 149,026,759 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2 C1.1|2 28.68 cM Start 49,509,310 bp[2] End 49,664,790 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Brodmann area 10 paraflocculus of cerebellum frontal pole cerebellar vermis middle temporal gyrus middle frontal gyrus Brodmann area 46 postcentral gyrus Brodmann area 23 orbitofrontal cortex Top expressed in globus pallidus substantia nigra cerebellar vermis lobe of cerebellum lateral geniculate nucleus dentate gyrus of hippocampal formation granule cell facial motor nucleus ventral tegmental area anterior amygdaloid area subiculum More reference expression data BioGPS n/a
Gene ontology Molecular function microtubule motor activity nucleotide binding microtubule binding protein binding plus-end-directed microtubule motor activity ATP binding ATPase activity Cellular component cytoplasm kinesin complex ciliary rootlet neuron projection microtubule cytoskeleton dendrite dendrite cytoplasm cell projection soma axonal growth cone synapse distal axon axon cytoplasm Biological process protein localization cytoskeleton-dependent intracellular transport mRNA transport organelle organization axon guidance microtubule-based movement motor neuron axon guidance synaptic vesicle transport anterograde dendritic transport of neurotransmitter receptor complex anterograde axonal protein transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3800 16574 Ensembl ENSG00000168280 ENSG00000276734 ENSMUSG00000026764 UniProt O60282 P28738 RefSeq (mRNA) NM_004522 NM_008449 RefSeq (protein) NP_004513 NP_032475 Location (UCSC) Chr 2: 148.88 – 149.03 Mb Chr 2: 49.51 – 49.66 Mb PubMed search [3] [4]
Wikidata
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