Keratin 9

Keratin 9 is a protein that in humans is encoded by the KRT9 gene.^[5][6]

AliasesKRT9, CK-9, EPPK, K9, keratin 9

External IDsOMIM: 607606; MGI: 96696; GeneCards: KRT9

Chr.Chromosome 17 (human)^[1]

End41,572,059 bp^[1]

Quick facts KRT9, Identifiers ...

KRT9
Identifiers
Aliases	KRT9, CK-9, EPPK, K9, keratin 9
External IDs	OMIM: 607606; MGI: 96696; GeneCards: KRT9
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.2 Start 41,565,836 bp[1] End 41,572,059 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 D Start 100,077,607 bp[2] End 100,084,072 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad human penis amniotic fluid gingival epithelium vulva skin of thigh skin of hip skin of abdomen muscle tissue Top expressed in genital tubercle dentate gyrus of hippocampal formation granule cell striatum of neuraxis superior frontal gyrus hippocampus proper primary visual cortex olfactory bulb cerebellar cortex thymus More reference expression data BioGPS n/a
Gene ontology Molecular function structural constituent of cytoskeleton structural molecule activity Cellular component extracellular exosome intermediate filament membrane nucleus extracellular space cytosol Biological process intermediate filament organization spermatogenesis skin development epidermis development keratinization cornification Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 3857 107656 Ensembl ENSG00000171403 ENSMUSG00000051617 UniProt P35527 Q6RHW0 RefSeq (mRNA) NM_000226 NM_201255 RefSeq (protein) NP_000217 NP_957707 Location (UCSC) Chr 17: 41.57 – 41.57 Mb Chr 11: 100.08 – 100.08 Mb PubMed search [3] [4]
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Keratin 9 is a type I cytokeratin. It is found only in the terminally differentiated epidermis of palms and soles. Mutations in the gene encoding this protein cause epidermolytic palmoplantar keratoderma.^[7]