Ketocaine

Chemical compound From Wikipedia, the free encyclopedia

Ketocaine (INN; brand name Vericaina; former developmental codes Astra 2358 and A-2358) is an amino ether local anesthetic of the butyrophenone family used topically for pain relief. It is marketed in Italy.[1][2][3]

ATC code
  • None
Quick facts Clinical data, ATC code ...
Ketocaine
Clinical data
ATC code
  • None
Identifiers
  • 1-[2-[2-[di(propan-2-yl)amino]ethoxy]phenyl]butan-1-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.012.847 Edit this at Wikidata
Chemical and physical data
FormulaC18H29NO2
Molar mass291.435 g·mol−1
3D model (JSmol)
  • CCCC(=O)C1=CC=CC=C1OCCN(C(C)C)C(C)C
  • InChI=InChI=1S/C18H29NO2/c1-6-9-17(20)16-10-7-8-11-18(16)21-13-12-19(14(2)3)15(4)5/h7-8,10-11,14-15H,6,9,12-13H2,1-5H3
  • Key:UXAWFWFJXIANHZ-UHFFFAOYSA-N
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Synthesis

Williamson ether synthesis between 2'-hydroxybutyrophenone (1) and diisopropylaminoethyl chloride (2) gives ketocaine (3).[4][5][6]

Synthesis of ketocaine

References

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