L1TD1

L1TD1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2LR6, 3SOO
Identifiers
Aliases	L1TD1, ECAT11, LINE-1 type transposase domain containing 1, LINE1 type transposase domain containing 1
External IDs	MGI: 3578435; HomoloGene: 136289; GeneCards: L1TD1; OMA:L1TD1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	62,212,328 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	98,626,717 bp
RNA expression pattern
	Top expressed in
	gonad; ; testicle; ; placenta; ; appendix; ; mucosa of transverse colon; ; white blood cell; ; monocyte; ; right testis; ; left testis; ; epithelium of colon;
	Top expressed in
	yolk sac; ; epiblast; ; embryo; ; blastocyst; ; blastocyst; ; primitive streak; ; morula; ; embryo; ; tail of embryo; ; hand;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	single-stranded RNA binding; protein binding;
Cellular component	ribonucleoprotein complex;
Biological process	transposition, RNA-mediated;
	Sources:Amigo / QuickGO
Orthologs
	54596
	381591
	ENSG00000240563
	ENSMUSG00000087166
	Q5T7N2
	Q587J6
	NM_019079; NM_001164835
	NM_001081202
	NP_001158307; NP_061952
	NP_001074671
	Wikidata
View/Edit Human	View/Edit Mouse

LINE-1 type transposase domain containing 1, also known as L1TD1, is an RNA-binding protein that involved with self-renewal of undifferentiated human embryonic stem cells and cancer cell proliferation. L1TD1 has been reported to associate with the development of several cancers. ^[5] ^[6] ^[7] ^[8]