LMO7

LIM domain only protein 7 is a protein that in humans is encoded by the LMO7 gene.^[5][6][7]

PDBHuman UniProt search: PDBe RCSB

AliasesLMO7, FBX20, FBXO20, LOMP, LIM domain 7, LMO7b

External IDsOMIM: 604362; MGI: 1353586; HomoloGene: 83924; GeneCards: LMO7; OMA:LMO7 - orthologs

Chr.Chromosome 13 (human)^[1]

Quick facts Available structures, PDB ...

LMO7
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2EAQ
Identifiers
Aliases	LMO7, FBX20, FBXO20, LOMP, LIM domain 7, LMO7b
External IDs	OMIM: 604362; MGI: 1353586; HomoloGene: 83924; GeneCards: LMO7; OMA:LMO7 - orthologs
Gene location (Human) Chr. Chromosome 13 (human)[1] Band 13q22.2 Start 75,620,434 bp[1] End 75,859,870 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14 E2.3|14 50.9 cM Start 101,729,957 bp[2] End 101,934,710 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve apex of heart right lung upper lobe of left lung right auricle of heart Achilles tendon left lobe of thyroid gland right lobe of thyroid gland olfactory zone of nasal mucosa stromal cell of endometrium Top expressed in zygote secondary oocyte Ileal epithelium cardiac muscle tissue of left ventricle primary oocyte corneal stroma interventricular septum left lung lobe conjunctival fornix right lung lobe More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding ubiquitin-protein transferase activity DNA-binding transcription factor activity Cellular component cytoplasm ubiquitin ligase complex nucleus focal adhesion cytosol nuclear envelope cell surface apical plasma membrane Biological process regulation of cell adhesion protein ubiquitination regulation of signaling protein polyubiquitination post-translational protein modification positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4008 380928 Ensembl ENSG00000136153 ENSMUSG00000033060 UniProt Q8WWI1 n/a RefSeq (mRNA) NM_001306080 NM_005358 NM_015842 NM_015843 NM_001330583 NM_201529 NM_001347628 RefSeq (protein) NP_001293009 NP_001317512 NP_005349 NP_056667 NP_001353561 NP_001353562 NP_001353563 NP_001353565 NP_001293009.1 n/a Location (UCSC) Chr 13: 75.62 – 75.86 Mb Chr 14: 101.73 – 101.93 Mb PubMed search [3] [4]
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This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain. An F-box (FBX) domain is present in alternative splice variants. Members of the LIM protein family carry the LIM domain, a unique cysteine-rich zinc-binding domain. Members of the FBX protein family are involved in protein-protein interactions. The encoded protein may be involved in protein-protein interactions. Multiple alternative splice variants have been described but their full-length sequences have not been determined.^[7]