LYAR

LYAR
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WJV
Identifiers
Aliases	LYAR, ZC2HC2, ZLy1 antibody reactive
External IDs	OMIM: 617684; MGI: 107470; HomoloGene: 41200; GeneCards: LYAR; OMA:LYAR - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	4,290,154 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	38,391,650 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; left testis; ; sperm; ; right testis; ; granulocyte; ; tendon of biceps brachii; ; monocyte; ; pericardium; ; lymph node; ; myocardium of left ventricle;
	Top expressed in
	otic placode; ; spermatid; ; otic vesicle; ; seminiferous tubule; ; spermatocyte; ; saccule; ; tail of embryo; ; epiblast; ; neural layer of retina; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; protein binding; RNA binding; DNA binding;
Cellular component	nucleus; nucleolus; photoreceptor outer segment; cytoplasm; cell projection;
Biological process	negative regulation of transcription by RNA polymerase II; rRNA processing; erythrocyte development; positive regulation of phagocytosis;
	Sources:Amigo / QuickGO
Orthologs
	55646
	17089
	ENSG00000145220
	ENSMUSG00000067367
	Q9NX58
	Q08288
	NM_001145725; NM_017816
	NM_025281
	NP_001139197; NP_060286
	NP_079557
	Wikidata
View/Edit Human	View/Edit Mouse

Cell growth-regulating nucleolar protein is a protein that in humans is encoded by the LYAR gene (Ly-1 antibody reactive clone).^[5]

PDBOrtholog search: PDBe RCSB

AliasesLYAR, ZC2HC2, ZLy1 antibody reactive

Quick facts Available structures, PDB ...

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LYAR contains a zinc finger motif and three copies of nuclear localization signals. LYAR is mainly localized to the nucleoli. LYAR is present at high levels in early embryos and preferentially in the liver fetal thymus.^[6]

References