Lexatumumab

Monoclonal antibody From Wikipedia, the free encyclopedia

Lexatumumab (also known as ETR2-ST01) is an experimental agonistic human monoclonal antibody against TRAIL-R2 (DR5, APO-2), intended for the treatment of cancer.[1][2]

TypeWhole antibody
TargetTRAIL-R2
ATC code
  • none
Quick facts Monoclonal antibody, Type ...
Lexatumumab
Monoclonal antibody
TypeWhole antibody
SourceHuman
TargetTRAIL-R2
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC6346H9832N1720O2002S42
Molar mass143601.02 g·mol−1
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HGS-ETR2 antibodies were generated by Human Genome Sciences through a collaboration with Cambridge Antibody Technology.[3]

Development was discontinued in 2015.[4]

References

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