Licochalcone A

Chemical compound From Wikipedia, the free encyclopedia

Licochalcone A is a chalconoid, a type of natural phenol. It can be isolated from the root of Glycyrrhiza glabra[2] (liquorice) or Glycyrrhiza inflata.[3] It shows antimalarial, anticancer, antibacterial and antiviral (specifically against influenza neuraminidase) properties in vitro.[2][3][4][5]

Quick facts Names, Identifiers ...
Licochalcone A
Chemical structure of licochalcone A
Chemical structure of licochalcone A
Names
Preferred IUPAC name
(2E)-3-[4-Hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
Other names
Licochalcone a
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.163.544 Edit this at Wikidata
EC Number
  • 635-678-2
UNII
  • InChI=1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+ ☒N
    Key: KAZSKMJFUPEHHW-DHZHZOJOSA-N ☒N
  • InChI=1/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+
    Key: KAZSKMJFUPEHHW-DHZHZOJOBU
  • CC(C)(C=C)c1cc(c(cc1O)OC)/C=C/C(=O)c2ccc(cc2)O
Properties
C21H22O4
Molar mass 338.403 g·mol−1
Hazards
GHS labelling:
GHS07: Exclamation mark[1]
Warning
H302, H312, H332[1]
P261, P264, P280[1]
Safety data sheet (SDS)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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