MAGED4B

Melanoma-associated antigen D4 is a protein that in humans is encoded by the MAGED4B gene.^[3]

AliasesMAGED4B, MAGE family member D4B

External IDsOMIM: 300765; HomoloGene: 52232; GeneCards: MAGED4B; OMA:MAGED4B - orthologs

Chr.X chromosome (human)^[1]

End52,069,219 bp^[1]

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MAGED4B
Identifiers
Aliases	MAGED4B, MAGE family member D4B
External IDs	OMIM: 300765; HomoloGene: 52232; GeneCards: MAGED4B; OMA:MAGED4B - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xp11.22 Start 52,061,827 bp[1] End 52,069,219 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone ganglionic eminence pituitary gland hypothalamus anterior pituitary nucleus accumbens amygdala caudate nucleus putamen hippocampus proper n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 81557 n/a Ensembl ENSG00000187243 n/a UniProt Q96JG8 n/a RefSeq (mRNA) NM_001242362 NM_030801 NM_177535 NM_177537 n/a RefSeq (protein) NP_001092270 NP_001258990 NP_001258991 NP_001258992 n/a Location (UCSC) Chr X: 52.06 – 52.07 Mb n/a PubMed search [2] n/a
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This gene is related to members of the MAGED gene family, in terms of the sequence similarity and the chromosome location. This gene is expressed only in brain and ovary among normal tissues, and two transcript variants of this gene are specifically expressed in glioma cells among cancer cells. This gene and the other MAGED genes are clustered on chromosome Xp11. Multiple alternatively spliced transcript variants have been found for this gene, however, the full length nature of some variants has not been defined.^[3]