MAP1A

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Microtubule-associated protein 1A is a protein that in humans is encoded by the MAP1A gene.[4][5][6]

AliasesMAP1A, MAP1L, MTAP1A, microtubule associated protein 1A
Chr.Chromosome 2 (mouse)[1]
End121,141,313 bp[1]
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MAP1A
Identifiers
AliasesMAP1A, MAP1L, MTAP1A, microtubule associated protein 1A
External IDsOMIM: 600178; MGI: 1306776; HomoloGene: 1778; GeneCards: MAP1A; OMA:MAP1A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002373

NM_001173506
NM_032393

RefSeq (protein)

NP_002364

NP_001166977
NP_115769

Location (UCSC)n/aChr 2: 121.12 – 121.14 Mb
PubMed search[2][3]
Wikidata
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Function

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain. Expression of this gene is almost exclusively in the brain. Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development.[6]

Interactions

MAP1A has been shown to interact with DISC1.[7]

References

Further reading

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