MAP1B
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Microtubule-associated protein 1B is a protein that in humans is encoded by the MAP1B gene.[5][6]
Function
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. Two alternatively spliced transcript variants have been described.[6]
Interactions
MAP1B has been shown to interact with Acidic leucine-rich nuclear phosphoprotein 32 family member A[7] and RASSF1.[8]
